There are new criteria that we are being told is extremely important when looking for signs of heart disease. The blood tests for these factors are very sophisticated and few labs are able to perform the testing.

Homocystine 
C-Reactive Protein 
Lipoprotein(a) 
Lipoprotein(IIb & IIIb) 
Fibrinogen 

The basics like Total Cholesterol, HDL, LDL, and Tryglycerides are still important but many people with good stats in this area were coming down with heart attacks.
Also, the liver supposedly has certain receptors, which determine the way your body metabolizes cholesterol. This is a genetic trait and that partially explains why some people can eat almost anything and others merely have to look at an egg yolk and their cholesterol level rises.